Agenda

Arrival, registration, and coffee

Summit introduction

Session 1. The evolving global footprint of dengue: implications, challenges, and opportunities

Session objective: to discuss how the recent changes in global DENV distribution impacts traditional assumptions regarding risk and control

Coffee break

Session 2. Beyond the first week: understanding long-term sequalae and persistent public-health impacts of dengue

Session objective: to explore new observations of dengue’s long term impact on patients, communities, and how each are challenging traditional assumptions of factors driving risk and opportunities for control

Lunch Break (boxed lunch)

Session 3. Reviving the discussion of dengue diagnostic development and applications to infection and disease surveillance

Session objective: to explore the current status of novel dengue diagnostics development and molecular surveillance efforts

Coffee break

Session 4. Genetics and dengue: virus, vector, and host

Session objective: to discuss and review what is known about virus, vector, and host genetics in regards to dengue transmission, immunity, and pathogenesis

Break

Session 5. Latest-breaking science, session #1

Happy hour and poster session (Grand Hall)

Arrival and coffee

Session 6. Advanced stage countermeasure update: vaccines

Session objective: to review and discuss the state of advanced-stage dengue countermeasures. Presentations from advanced-stage countermeasure developers.

Coffee break

Session 7. Advanced stage countermeasure update: therapeutics

Session objective: to review and discuss the state of advanced-stage dengue countermeasures. Presentations from advanced-stage countermeasure developers.

Coffee break

Session 8. Advanced stage countermeasure update: vector control

Session objective: to review and discuss the state of advanced-stage dengue countermeasures. Presentations from advanced-stage countermeasure developers.

Lunch Break (boxed lunch)

Session 9. Moving beyond antibodies: cellular and innate immunity in dengue

Session objective: to discuss the contribution of cellular and innate immunity in dengue immunity and pathogenesis

Coffee Break

Session 10. Non-DENV flavivirus immune cross-talk: when/why does it matter?

Session objective: to review and discuss how and when non-DENV flavivirus immunity impacts DENV immunity and pathogenesis

Break

Session 11. Panel discussion: why do (some) people get (very) sick with dengue?

Session objective: to interactively discuss and debate current models of dengue immunity and pathogenesis, with a focus on how the evolution of these models may inform a dengue endgame

Group photo and closing remarks, Day 2

Social event (RiverTrail Beerworks)

Arrival and coffee

Session 12. Panel discussion #2: regulatory challenges and opportunities in pursuit of a dengue endgame

Session objective: to discuss current regulatory challenges and opportunities that are either limiting or advancing progress towards a dengue endgame

Coffee break

Session 13. Cross-field fertilization: what can the dengue field learn from the successes and failures of other infectious disease control efforts?

Session objective: to discuss and review how the dengue field can learn from the successes and failures of other global infectious disease control efforts

Lunch Break (boxed lunch)

Session 14. The last mile: ensuring accurate science reaches those who need it most

Session objective: to discuss the role of science communication in global and local dengue control efforts

Coffee Break

Session 15. Local solution to a global challenge

Session objective: to highlight, review, and discuss locally-tailored dengue control efforts

Session 16. Panel discussion #3: where do we go from here? Leadership and global coordination in pursuit of a dengue endgame

Session objective: to discuss the need for global coordination and leadership in pursuit of a dengue endgame

Closing remarks